BDBM50395565 CHEMBL160357

SMILES c1ccc(cc1)N2CCN(CC2)CCCCOc3ccc4c(c3)NC(=O)CC4

InChI Key InChIKey=USIMZAIRLDAIQJ-UHFFFAOYSA-N

Data  1 KI  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50395565   

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395565(CHEMBL160357)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at D2L receptor in human HTLA cells assessed as beta arrestin recruitment at 6 uM after 18 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395565(CHEMBL160357)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human D2L receptor expressed in HEK293T cells coexpressing Gi subunit assessed as inhibition of isoproterenol-stimulated cAMP pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395565(CHEMBL160357)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed