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BDBM50395784 CHEMBL2164851

SMILES: O=C(Nc1cc(c[nH]c1=O)-c1ccncc1)[C@H](Cc1ccccc1)NC1(CC1)c1ncccn1

InChI Key: InChIKey=WJWWGOFGWOKXSL-QFIPXVFZSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395784   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Probable G-protein coupled receptor 142


(Homo sapiens (Human))
BDBM50395784
PNG
(CHEMBL2164851)
Show SMILES O=C(Nc1cc(c[nH]c1=O)-c1ccncc1)[C@H](Cc1ccccc1)NC1(CC1)c1ncccn1
Show InChI InChI=1S/C26H24N6O2/c33-23-21(16-20(17-30-23)19-7-13-27-14-8-19)31-24(34)22(15-18-5-2-1-3-6-18)32-26(9-10-26)25-28-11-4-12-29-25/h1-8,11-14,16-17,22,32H,9-10,15H2,(H,30,33)(H,31,34)/t22-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 99n/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation after 1 hr by scintillation counting


Bioorg Med Chem Lett 22: 6218-23 (2012)


Article DOI: 10.1016/j.bmcl.2012.08.015
BindingDB Entry DOI: 10.7270/Q2CN751R
More data for this
Ligand-Target Pair