BDBM50026636 17alpha-hydroxy-20alpha-yohimban-16beta-carboxylic acid methyl ester::CHEMBL10347::RAUWOLSCINE HYDROCHLORIDE::alpha-yohimbine::corynanthidine::isoyohimbine::mesoyohimbine::methyl (16beta,17alpha,20alpha)-17-hydroxyyohimban-16-carboxylate::methyl 17alpha-hydroxy-20alpha-yohimban-16beta-carboxylate::rauwolscine

SMILES: COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12

InChI Key: InChIKey=BLGXFZZNTVWLAY-UHFFFAOYSA-N

Data: 33 KI  6 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 41 hits for monomerid = 50026636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-2C adrenergic receptor (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Adenosine receptor A2b (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	13.8	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Adenosine receptor A2b (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Horse)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cholinesterase (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-1B adrenergic receptor (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-2C adrenergic receptor (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-2B adrenergic receptor (Dog)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-2A adrenergic receptor (Bovine)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Guinea pig)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Guinea pig)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-2A adrenergic receptor (Bovine)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-1D adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Voltage-dependent L-type calcium channel subunit alpha-1C (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		149	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Dog)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Bovine)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Bovine)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rabbit)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rabbit)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rabbit)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM50026636 (RAUWOLSCINE HYDROCHLORIDE | 17alpha-hydroxy-20alph...) Show SMILES Show InChI	GoogleScholar	UniChem		4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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