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BDBM50396030 CHEMBL2169991

SMILES: Fc1ccc2CCN(C(=O)Nc3cc(OC(F)(F)F)cc(c3)-c3cccnc3)c2c1

InChI Key: InChIKey=RHIYEYUIUMSPGC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396030   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50396030
PNG
(CHEMBL2169991)
Show SMILES Fc1ccc2CCN(C(=O)Nc3cc(OC(F)(F)F)cc(c3)-c3cccnc3)c2c1
Show InChI InChI=1S/C21H15F4N3O2/c22-16-4-3-13-5-7-28(19(13)10-16)20(29)27-17-8-15(14-2-1-6-26-12-14)9-18(11-17)30-21(23,24)25/h1-4,6,8-12H,5,7H2,(H,27,29)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 600n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...


ACS Med Chem Lett 3: 373-377 (2012)


Article DOI: 10.1021/ml300008j
BindingDB Entry DOI: 10.7270/Q2PZ59X6
More data for this
Ligand-Target Pair