BDBM50396152 CHEMBL2171741::US8802674, 232

SMILES CNc1nc(Nc2ccc(cc2C)C(=O)N2CCOCC2)ncc1Cl

InChI Key InChIKey=QUNPHSMWVSWDRP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396152   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50396152(CHEMBL2171741 | US8802674, 232)
Affinity DataKi:  7nMAssay Description:Inhibition of LRRK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50396152(CHEMBL2171741 | US8802674, 232)
Affinity DataKi:  7.40nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50396152(CHEMBL2171741 | US8802674, 232)
Affinity DataKi: >3.20E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed