BDBM50396534 CHEMBL2171124

SMILES: Cn1cc(-c2ccc3N(CCc3c2)C(=O)Cc2cccc(c2)C(F)(F)F)c2c(N)ncnc12

InChI Key: InChIKey=SIXVRXARNAVBTC-UHFFFAOYSA-N

Data: 32 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50396534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NT-3 growth factor receptor (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 2-alpha kinase 3 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 2-alpha kinase 1 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
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Interferon-induced, double-stranded RNA-activated protein kinase (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	696	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 6 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 10 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	452	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Mer (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	474	n/a	n/a	n/a	n/a	n/a	n/a
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Discoidin domain-containing receptor 2 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	524	n/a	n/a	n/a	n/a	n/a	n/a
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Myosin light chain kinase 2, skeletal/cardiac muscle (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	701	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit epsilon (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 11 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Nek4 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 5 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 9 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase receptor UFO (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
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BDNF/NT-3 growth factors receptor (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Yes (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase WNK2 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 2-alpha kinase 3 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 2-alpha kinase 3 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM50396534 (CHEMBL2171124) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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