BDBM50396555 CHEMBL2171396

SMILES COc1cc(nn1-c1ccccc1F)C(=O)N[C@@H](CC(O)=O)c1ccccc1C

InChI Key InChIKey=RQQTYVIPHKLYFS-INIZCTEOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396555   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50396555(CHEMBL2171396)
Affinity DataIC50:  26nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50396555(CHEMBL2171396)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant NEP using Mca-RPPGFSAFK(Dnp)-OH as substrate incubated for 15 mins prior to substrate addition measured after 20 to 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal protective protein(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50396555(CHEMBL2171396)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed