BDBM50396641 CHEMBL2171942

SMILES CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CC(C3)C3CCOCC3)n(C)c2n1

InChI Key InChIKey=FUKXEHFNLZECLC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396641   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50396641(CHEMBL2171942)Copy SMILESCopy InChI

Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant PI3Kdelta assessed as inhibition of PIP3 production for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI