BDBM50397415 CHEMBL2170703

SMILES COc1cc2O[C@]3([C@@H]([C@H]([C@@H](O)[C@@]3(O)c2c(OC)c1)C(=O)N(C)C)c1ccccc1)c1ccc(cc1)C#N

InChI Key InChIKey=CKHVREJQHBANOJ-IDAMAFBJSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397415   

TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50397415(CHEMBL2170703)
Affinity DataEC50:  40nMAssay Description:Inhibition of eIF4FA in human MDA-MB-231 cells transfected with tubulin 5'-UTR-luciferase construct assessed as reduction in translation initiation i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50397415(CHEMBL2170703)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of eIF4FA in human MDA-MB-231 cells transfected with c-myc- 5'-UTR-luciferase construct assessed as reduction in translation initiation in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed