BDBM50397420 CHEMBL2170563

SMILES COc1ccc(cc1)[C@@]12Oc3cc(Cl)cc(OC)c3[C@]1(O)[C@H](O)[C@@H]([C@H]2c1ccccc1)C(=O)N(C)C

InChI Key InChIKey=QGAOOBALZRBQLX-GWNOIRNCSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397420   

TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50397420(CHEMBL2170563)
Affinity DataEC50:  15nMAssay Description:Inhibition of eIF4FA in human MDA-MB-231 cells transfected with tubulin 5'-UTR-luciferase construct assessed as reduction in translation initiation i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50397420(CHEMBL2170563)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of eIF4FA in human MDA-MB-231 cells transfected with c-myc- 5'-UTR-luciferase construct assessed as reduction in translation initiation in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed