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BDBM50397449 CHEMBL2170832

SMILES: CC(CNCc1ccc(O)c(F)c1)[C@H]1CCC2=Cc3c(O[C@H]2C1)cc(C)oc3=O

InChI Key: InChIKey=YVZIHEXHPIHHAQ-KURWCMQDNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50397449   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase 1


(Homo sapiens (Human))
BDBM50397449
PNG
(CHEMBL2170832)
Show SMILES CC(CNCc1ccc(O)c(F)c1)[C@H]1CCC2=Cc3c(O[C@H]2C1)cc(C)oc3=O
Show InChI InChI=1/C23H26FNO4/c1-13(11-25-12-15-3-6-20(26)19(24)8-15)16-4-5-17-9-18-22(29-21(17)10-16)7-14(2)28-23(18)27/h3,6-9,13,16,21,25-26H,4-5,10-12H2,1-2H3/t13?,16-,21-/s2
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Kansas State University

Curated by ChEMBL


Assay Description
Inhibition of ACAT activity in human MC65 cells using NBD-cholesterol staining after 48 hrs by fluorescence assay


J Med Chem 55: 8969-73 (2012)


Article DOI: 10.1021/jm3012189
BindingDB Entry DOI: 10.7270/Q2000370
More data for this
Ligand-Target Pair