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BDBM50397450 CHEMBL2170821

SMILES: CC(CNCc1ccc(CO)cc1)[C@H]1CCC2=Cc3c(O[C@H]2C1)cc(C)oc3=O

InChI Key: InChIKey=VOSGBTIUAVXGTR-BNDPDNPJNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50397450   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase 1


(Homo sapiens (Human))
BDBM50397450
PNG
(CHEMBL2170821)
Show SMILES CC(CNCc1ccc(CO)cc1)[C@H]1CCC2=Cc3c(O[C@H]2C1)cc(C)oc3=O
Show InChI InChI=1/C24H29NO4/c1-15(12-25-13-17-3-5-18(14-26)6-4-17)19-7-8-20-10-21-23(29-22(20)11-19)9-16(2)28-24(21)27/h3-6,9-10,15,19,22,25-26H,7-8,11-14H2,1-2H3/t15?,19-,22-/s2
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Kansas State University

Curated by ChEMBL


Assay Description
Inhibition of ACAT activity in human MC65 cells using NBD-cholesterol staining after 48 hrs by fluorescence assay


J Med Chem 55: 8969-73 (2012)


Article DOI: 10.1021/jm3012189
BindingDB Entry DOI: 10.7270/Q2000370
More data for this
Ligand-Target Pair