BDBM50397733 CHEMBL2181982

SMILES Brc1cc(COC(=O)[C@H]2C[C@]3(CN2)C(=O)Nc2ccccc32)ccc1C#N

InChI Key InChIKey=DJYALAFSFGHFLN-YLJYHZDGSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397733   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50397733(CHEMBL2181982)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant BACE1 using NH-SEVNLAAEF-COOH as substrate after 30 mins by NMR analysisMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50397733(CHEMBL2181982)
Affinity DataIC50:  6.26E+3nMAssay Description:Inhibition of human recombinant BACE1 using RGLTTRPGSGLTNIKTEEISEVNLDAEFRHDSGA as substrate after 1 hr by TMB-ELISAMore data for this Ligand-Target Pair