BDBM50397740 CHEMBL2181988

SMILES O=C1Nc2ccccc2[C@]11CCNC1

InChI Key InChIKey=FQSHLSLQUHZOMV-LLVKDONJSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397740   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50397740(CHEMBL2181988)
Affinity DataKd:  1.40E+6nMAssay Description:Inhibition of recombinant BACE1 binding to biotinylated stat-val peptide after 6 mins by octet assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50397740(CHEMBL2181988)
Affinity DataIC50:  1.10E+6nMAssay Description:Inhibition of recombinant BACE1 using NH-SEVNLAAEF-COOH as substrate after 30 mins by NMR analysisMore data for this Ligand-Target Pair