BDBM50397919 CHEMBL2179557
SMILES Fc1ccc(o1)C(=O)N1C[C@@H]2CN[C@H](C2)C1
InChI Key InChIKey=SCQZRFDFSKEVKQ-JGVFFNPUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50397919
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]nicotine from alpha4beta2 nAChR in human SH-EP1 cells after 2 hrs by liquid scintillation assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 2.10E+3nMAssay Description:Agonist activity at alpha4beta2 nAChR in human SH-EP1 cells assessed as calcium flux by calcium4-based FLIPR assayMore data for this Ligand-Target Pair