BDBM50397991 CHEMBL2180408

SMILES COCCc1ccc(cn1)-c1c(C)nc2c(ccnn12)N1CCOCC1

InChI Key InChIKey=BPLVDYJDAVYLRQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397991   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))TBA

LigandBDBM50397991(CHEMBL2180408)Copy SMILESCopy InChI

Affinity DataIC50:  58nMAssay Description:Inhibition of PDE10A2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails PubMed
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TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL

LigandBDBM50397991(CHEMBL2180408)Copy SMILESCopy InChI

Affinity DataIC50:  58nMAssay Description:Inhibition of rat recombinant PDE10A2 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 60 mins by scintillation proximi...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI