BDBM50397997 CHEMBL2180801::Roche-Dataset for PDE10A, Compound 1085::US8703768, 1

SMILES: Cn1cc(c(n1)C(=O)N(C)C)NC(=O)c2c(ccc(n2)C3CC3)Nc4cncnc4

InChI Key: InChIKey=NJOKFSSRVZAHBG-UHFFFAOYSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50397997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50397997 (CHEMBL2180801 | US8703768, 1 | Roche-Dataset for P...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50397997 (CHEMBL2180801 | US8703768, 1 | Roche-Dataset for P...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50397997 (CHEMBL2180801 | US8703768, 1 | Roche-Dataset for P...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair