BDBM50398007 CHEMBL2180428::US8691827, I-1

SMILES O=C(Nc1ccccc1)N1CCc2nc(nc(NCCc3ccccn3)c2C1)-c1ccncc1

InChI Key InChIKey=QISVXXJKNHGEBH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398007   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50398007(CHEMBL2180428 | US8691827, I-1)
Affinity DataKi:  47.9nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50398007(CHEMBL2180428 | US8691827, I-1)
Affinity DataKi:  48nMAssay Description:Inhibition of PDE10A by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed