BindingDB logo
myBDB logout

BDBM50398183 CHEMBL2182106

SMILES: CC(C)(C)c1ccc(cc1)C(=O)Nc1cc(Nc2ccc3c(CCCCC3=O)c2)ccc1F

InChI Key: InChIKey=HWYSYZLDBKHUKX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398183   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50398183
PNG
(CHEMBL2182106)
Show SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1cc(Nc2ccc3c(CCCCC3=O)c2)ccc1F
Show InChI InChI=1S/C28H29FN2O2/c1-28(2,3)20-10-8-18(9-11-20)27(33)31-25-17-22(13-15-24(25)29)30-21-12-14-23-19(16-21)6-4-5-7-26(23)32/h8-17,30H,4-7H2,1-3H3,(H,31,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Eberhard Karls University T£bingen

Curated by ChEMBL


Assay Description
Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2


J Med Chem 55: 7862-74 (2012)


Article DOI: 10.1021/jm300951u
BindingDB Entry DOI: 10.7270/Q22J6D1F
More data for this
Ligand-Target Pair