BDBM50398244 CHEMBL609728

SMILES Cc1ccc(NCCCN)c(c1)[N+]([O-])=O

InChI Key InChIKey=FKZUPMCBVURANR-UHFFFAOYSA-N

Data  3 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398244   

TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50398244(CHEMBL609728)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of biotinylated Tat-KAc50 peptide binding to PCAFMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50398244(CHEMBL609728)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of biotinylated Tat-AcK50 binding to GST-fused PCAF bromodomain (719 to 832 residues) (unknown origin) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate HXB2 ...)
TBA

Curated by ChEMBL
LigandPNGBDBM50398244(CHEMBL609728)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of Tat-mediated transcription of viral promoter in 293 T cells transfected with HIV1 tat by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50398244(CHEMBL609728)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of biotinylated small molecule ligand from His/FLAG-tagged PCAF bromodomain (719 to 832 residues) (unknown origin) after 15 mins by Alph...More data for this Ligand-Target Pair