BDBM50398327 VARIOLIN B

SMILES Nc1nccc(n1)-c1c2ccnc(N)n2c2nccc(O)c12

InChI Key InChIKey=RTHKPHCVZVYDFN-UHFFFAOYSA-N

Data  1 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398327   

TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50398327(VARIOLIN B)
Affinity DataEC50:  700nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed