BDBM50398361 CHEMBL2177372

SMILES CC(C)NC[C@@H](C(=O)N1CCN(CC1)c1ncnc2[C@H](O)C[C@@H](C)c12)c1ccc(Cl)c(F)c1

InChI Key InChIKey=ACYVWONXYYNPDK-WRWLIDTKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398361   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398361(CHEMBL2177372)
Affinity DataIC50:  3nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt1 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398361(CHEMBL2177372)
Affinity DataIC50:  17nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt2 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398361(CHEMBL2177372)
Affinity DataIC50:  7nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt3 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398361(CHEMBL2177372)
Affinity DataIC50:  234nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt1 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed