BDBM50398743 CHEMBL2179631

SMILES COc1ccc(cc1-c1cccc(COc2ccc3C(=O)N(Cc3c2)C2CCCC2)c1)C(O)=O

InChI Key InChIKey=BUZSAAKSFZMGDU-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50398743   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulation activity at rat mGlu2R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu8R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu7R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu1R expressed in HEK293 cells co-expressing GIRK channels by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu5R expressed in HEK293 cells co-expressing GIRK channels by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu4R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu6R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed