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BDBM50399201 CHEMBL2180147

SMILES: Cc1ccc(Cn2c3ccccc3c(=O)c3ccccc23)cc1

InChI Key: InChIKey=BVTPLBHYWFRLMF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399201   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 4


(Homo sapiens (Human))
BDBM50399201
PNG
(CHEMBL2180147)
Show SMILES Cc1ccc(Cn2c3ccccc3c(=O)c3ccccc23)cc1
Show InChI InChI=1S/C21H17NO/c1-15-10-12-16(13-11-15)14-22-19-8-4-2-6-17(19)21(23)18-7-3-5-9-20(18)22/h2-13H,14H2,1H3
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Similars

Article
PubMed
n/an/a 1.18E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human P2X4 receptor expressed in 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx compound preincub...


J Med Chem 55: 9576-88 (2012)


Article DOI: 10.1021/jm300845v
BindingDB Entry DOI: 10.7270/Q2XK8GPN
More data for this
Ligand-Target Pair