BDBM50399301 CHEMBL2180862

SMILES O=C(Nc1ccccn1)Nc1cccc2C(=O)N3CCCCC3c12

InChI Key InChIKey=KVVMSGAISWJACO-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50399301   

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399301(CHEMBL2180862)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399301(CHEMBL2180862)
Affinity DataIC50:  75nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399301(CHEMBL2180862)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST fused human recombinant DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by scintillation counting in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50399301(CHEMBL2180862)
Affinity DataIC50:  170nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399301(CHEMBL2180862)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma-33P]-ATP after 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399301(CHEMBL2180862)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399301(CHEMBL2180862)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed