BDBM50399615 CHEMBL2181171

SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1

InChI Key InChIKey=MREMSPSMZSVSJS-UHFFFAOYSA-N

Data  13 KI  1 EC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50399615   

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi:  13.1nMAssay Description:Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi:  627nMAssay Description:Binding affinity to human 5HT2B by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi:  680nMAssay Description:Binding affinity to human 5HT3 by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi:  2.79E+3nMAssay Description:Binding affinity to human 5HT2C by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT1B by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT1A by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT1E by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT2A by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT5A by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT6 by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT7 by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT1D by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataEC50:  10nMAssay Description:Inverse agonist activity at human recombinant 5HT4R expressed in HEK293T cells assessed as Gs activationMore data for this Ligand-Target Pair