BDBM50399620 CHEMBL2181187

SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1

InChI Key InChIKey=OLINRUQQUFMPJJ-UHFFFAOYSA-N

Data  13 KI  1 EC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50399620   

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi:  17nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi:  29.3nMAssay Description:Binding affinity to human 5HT2B by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi:  35nMAssay Description:Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi:  2.57E+3nMAssay Description:Binding affinity to human 5HT1D by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi:  3.47E+3nMAssay Description:Binding affinity to human 5HT7 by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi:  5.96E+3nMAssay Description:Binding affinity to human 5HT2A by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT1A by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT1E by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT2C by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT3 by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT5A by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT6 by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT1B by Cerep protocol based assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399620(CHEMBL2181187)
Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3
Affinity DataEC50:  79.4nMAssay Description:Inverse agonist activity at human recombinant 5HT4R expressed in HEK293T cells assessed as Gs activationMore data for this Ligand-Target Pair