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BDBM50399647 CHEMBL2177670

SMILES: OC(=O)C(C(CC(=O)c1ccc(I)cc1)c1ccccc1)C(O)=O

InChI Key: InChIKey=RLEQHNWKPHJQER-UHFFFAOYNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399647   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
3-phosphoinositide dependent protein kinase-1


(Homo sapiens (Human))
BDBM50399647
PNG
(CHEMBL2177670)
Show SMILES OC(=O)C(C(CC(=O)c1ccc(I)cc1)c1ccccc1)C(O)=O
Show InChI InChI=1/C18H15IO5/c19-13-8-6-12(7-9-13)15(20)10-14(11-4-2-1-3-5-11)16(17(21)22)18(23)24/h1-9,14,16H,10H2,(H,21,22)(H,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.00E+4n/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Increase in thermal stability of PDK1 by differential scanning fluorimetry


J Med Chem 55: 9817-30 (2012)


Article DOI: 10.1021/jm3010477
BindingDB Entry DOI: 10.7270/Q2PV6MHW
More data for this
Ligand-Target Pair