BDBM50399656 CHEMBL2069623::US11633415, Compound PF4800567

SMILES Nc1ncnc2n(nc(COc3cccc(Cl)c3)c12)C1CCOCC1

InChI Key InChIKey=AUMDBEHGJRZSOO-UHFFFAOYSA-N

Data  9 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50399656   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50:  711nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50:  32nMAssay Description:Inhibition of CK1epsilonMore data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50:  711nMAssay Description:Inhibition of Casein kinase 1 deltaMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50:  32nMAssay Description:Inhibition of Casein kinase 1 epsilonMore data for this Ligand-Target Pair
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50:  857nMAssay Description:In order to identify inhibitors of CSNK1A1, the CSNK1A1 knockdown signatures in CMap were compared to all CMap compound signatures, and resultant com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50:  32nMAssay Description:Inhibition of human full length CK1delta1 (2 to 415 residues) using PLSRTLpSVASLPGL as substrate after 2 hrs by kinase-glo assayMore data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50:  711nMAssay Description:Inhibition of human CK1delta in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50:  32nMAssay Description:Inhibition of human CK1epsilon in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50:  32nMAssay Description:Inhibition of human full length polyhistidine-tagged CK1epsilon expressed in Escherichia coli BL21-Codon-Plus (DE3)-RIL using PLSRTLpSVASLPGL as subs...More data for this Ligand-Target Pair