BDBM50399881 CHEMBL2180639
SMILES Oc1cccc(CCN(CCc2ccccc2)CC2CCC2)c1
InChI Key InChIKey=YNVKFHIWFDRVNY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50399881
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-HS665 from KOR in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 282nMAssay Description:Displacement of [3H]YM-09151-2 from human dopamine D3 receptor expressed in CHOp cellsMore data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Displacement of [3H]YM-09151-2 from human dopamine D2 receptor expressed in CHOp cellsMore data for this Ligand-Target Pair
Affinity DataKi: 542nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]pCl-DPDPE from human delta opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in LHD1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 463nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as increase in beta-arrestin 2 recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.60nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 953nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as inhibition of quinpirol-induced mitogenesis incubated for 24 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+3nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as inhibition of quinpirol-induced mitogenesis incubated for 24 hr...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as stimulation of mitogenesis incubated for 24 hrs by [3H]thymidine i...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as stimulation of mitogenesis incubated for 24 hrs by [3H]thymidine i...More data for this Ligand-Target Pair