BDBM50400739 CHEMBL2203550

SMILES Clc1cncc(OCc2cc(OC[C@@H]3CCN3)no2)c1

InChI Key InChIKey=WDBLHIYRGWVIPR-JTQLQIEISA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50400739   

LigandPNGBDBM50400739(CHEMBL2203550)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor; alpha2/beta4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400739(CHEMBL2203550)
Affinity DataKi:  1.82E+3nMAssay Description:Displacement of [3H]epibatidine from alpha2beta4 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400739(CHEMBL2203550)
Affinity DataKi:  2.22E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400739(CHEMBL2203550)
Affinity DataKi:  5.58E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400739(CHEMBL2203550)
Affinity DataKi:  6.10E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3beta4 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400739(CHEMBL2203550)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50400739(CHEMBL2203550)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2* nAChR in rat forebrain after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400739(CHEMBL2203550)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from alpha2beta2 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed