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BDBM50400769 CHEMBL2204977

SMILES: CS(=O)(=O)N1CCC(=CC1)c1cc2C[C@@H](Oc2cn1)C1CCN(CC1)c1ncc(cn1)C1CC1

InChI Key: InChIKey=GPHDDBOESAIKHK-QWVACARCNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400769   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM50400769
PNG
(CHEMBL2204977)
Show SMILES CS(=O)(=O)N1CCC(=CC1)c1cc2C[C@@H](Oc2cn1)C1CCN(CC1)c1ncc(cn1)C1CC1
Show InChI InChI=1/C25H31N5O3S/c1-34(31,32)30-10-6-18(7-11-30)22-12-20-13-23(33-24(20)16-26-22)19-4-8-29(9-5-19)25-27-14-21(15-28-25)17-2-3-17/h6,12,14-17,19,23H,2-5,7-11,13H2,1H3/t23-/s2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in MIN6 cells assessed as intracellular cAMP concentration after 45 mins by Alphascreen analysis


ACS Med Chem Lett 3: 955-958 (2012)


Article DOI: 10.1021/ml300296q
BindingDB Entry DOI: 10.7270/Q2SB46WV
More data for this
Ligand-Target Pair