BDBM50401097 CHEMBL2204469

SMILES Cc1c(Cc2ccc(=O)n(Cc3ccc(F)cc3F)n2)c2cc(F)ccc2n1CC(O)=O

InChI Key InChIKey=ZTPOWDSDKMQVBU-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50401097   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human recombinant CRTh2 expressed in CHO-K1 cells by cAMP TR FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  5.60E+5nMAssay Description:Antagonist activity at TXA2 receptor by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP2A6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  0.800nMAssay Description:Binding affinity to human CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]PGD2 from recombinant human CRTH2 receptor expressed in CHO-K1 cells after 30 min by FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  1.90E+4nMAssay Description:Binding affinity to DP1 receptor by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  7nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP2B6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of CRTH2 receptor-mediated chemotaxis in human basophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed