BDBM50401154 CHEMBL2205775

SMILES COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1cncn1

InChI Key InChIKey=RFXXESOWGZZTJX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50401154   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50401154(CHEMBL2205775)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50401154(CHEMBL2205775)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50401154(CHEMBL2205775)
Affinity DataIC50:  13nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA as substrate after 1 hr by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50401154(CHEMBL2205775)
Affinity DataIC50:  200nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50401154(CHEMBL2205775)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50401154(CHEMBL2205775)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed