BDBM50401506 CHEMBL2205895

SMILES C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C(C)(C)c5c(C[C@]4(C)[C@H]3CC[C@]12C)cnn5-c1ccccc1

InChI Key InChIKey=RKKANVCCOGLUFB-DAMQFFQQSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50401506   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50401506(CHEMBL2205895)
Affinity DataKi:  840nMAssay Description:Competitive inhibition of PTP1B by para-nitrophenyl phosphate release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Cricetulus griseus)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50401506(CHEMBL2205895)
Affinity DataEC50:  8.80E+3nMAssay Description:Induction of degradation of hamster HMGCR (TM1-8)-GFP (1 to 346 residues) transfected in CHO-7 cells incubated for 16 hrs in sterol-depleted medium b...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50401506(CHEMBL2205895)
Affinity DataIC50:  2.28E+4nMAssay Description:Inhibition of TCPTP by para-nitrophenyl phosphate release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50401506(CHEMBL2205895)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of PTP1B by para-nitrophenyl phosphate release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed