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BDBM50401575 CHEMBL2207118

SMILES: Cc1ccc(cc1)-n1ncc(Cl)c(Oc2ccc(O)cc2)c1=O

InChI Key: InChIKey=FMFCQSRXVMJDLE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401575   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
neuropeptides B/W receptor 1


(Homo sapiens (Human))
BDBM50401575
PNG
(CHEMBL2207118)
Show SMILES Cc1ccc(cc1)-n1ncc(Cl)c(Oc2ccc(O)cc2)c1=O
Show InChI InChI=1S/C17H13ClN2O3/c1-11-2-4-12(5-3-11)20-17(22)16(15(18)10-19-20)23-14-8-6-13(21)7-9-14/h2-10,21H,1H3
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UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human NPBWR1 expressed in HEK293T cells co-expressing Galphaqi3 assessed as calcium release after 15 mins by FLIPR assay assay


Bioorg Med Chem Lett 22: 7135-41 (2012)


Article DOI: 10.1016/j.bmcl.2012.09.074
BindingDB Entry DOI: 10.7270/Q2WS8VDC
More data for this
Ligand-Target Pair