BDBM50401910 CHEMBL2207217

SMILES Brc1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)c1cccs1

InChI Key InChIKey=DLUFUVCAUGKHRL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50401910   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50401910(CHEMBL2207217)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [gamma33P]ATP from human TBK1 expressed in insect sf21 cells measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50401910(CHEMBL2207217)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of human IKKepsilon expressed in insect sf21 cells using MBP as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401910(CHEMBL2207217)
Affinity DataIC50:  6nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50401910(CHEMBL2207217)
Affinity DataIC50:  11nMAssay Description:Displacement of [gamma33P]ATP from human PDK1 expressed in insect sf21 cells measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50401910(CHEMBL2207217)
Affinity DataIC50:  26nMAssay Description:Inhibition of PDK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50401910(CHEMBL2207217)
Affinity DataIC50:  11nMAssay Description:Inhibition of human Aurora B expressed in insect sf21 cells using LRRLSLGLRRLSLGLRRLSLGLRRLSLG peptide as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed