BDBM50401910 CHEMBL2207217
SMILES Brc1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)c1cccs1
InChI Key InChIKey=DLUFUVCAUGKHRL-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50401910
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Displacement of [gamma33P]ATP from human TBK1 expressed in insect sf21 cells measured for 30 minsMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human IKKepsilon expressed in insect sf21 cells using MBP as substrate measured for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of [gamma33P]ATP from human PDK1 expressed in insect sf21 cells measured for 30 minsMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of PDK1 by radiometryMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human Aurora B expressed in insect sf21 cells using LRRLSLGLRRLSLGLRRLSLGLRRLSLG peptide as substrate measured for 30 minsMore data for this Ligand-Target Pair