BDBM50402020 CHEMBL2205426

SMILES: CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(cc3)-c3ccncc3)n2)c(=O)c1=O

InChI Key: InChIKey=NDIUYMHNCUTVGE-UHFFFAOYSA-N

Data: 60 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 61 hits for monomerid = 50402020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK4 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		167	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycystin-2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
LIM domain kinase 1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		194	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Rho-associated protein kinase 1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		262	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase subunit beta-1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		333	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 5 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		416	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		494	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ribosomal protein S6 kinase alpha-3 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase ABL1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Blk (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Fibroblast growth factor receptor 3 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase Lyn (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Hepatocyte growth factor receptor (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Insulin-like growth factor 1 receptor (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ephrin type-A receptor 2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase MARK2 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		3.61E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cell division control protein 42 homolog (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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BDNF/NT-3 growth factors receptor (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		>4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP/microtubule affinity-regulating kinase 3 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		4.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Mitogen-activated protein kinase 13 (Human)	BDBM50402020 (CHEMBL2205426) Show SMILES Show InChI	GoogleScholar	UniChem		5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair