BDBM50402023 BI 6727::VOLASERTIB

SMILES: CC[C@H]1N(C(C)C)c2nc(Nc3ccc(cc3OC)C(=O)N[C@H]3CC[C@@H](CC3)N3CCN(CC4CC4)CC3)ncc2N(C)C1=O

InChI Key: InChIKey=SXNJFOWDRLKDSF-UHFFFAOYSA-N

Data: 12 IC50  8 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50402023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	255	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Wee1-like protein kinase (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Wee1-like protein kinase (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	317	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM50402023 (BI 6727 | VOLASERTIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair