BDBM50403974 CHEMBL84931

SMILES CN(C)CC1CC2N(O1)c1cc(F)ccc1Cc1ccccc21

InChI Key InChIKey=MSQRTETUBFIHMP-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50403974   

TargetHistamine H1 receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  2.60nMAssay Description:Binding affinity at human cloned Histamine H1 receptor expressed in CHO cells by [3H]pyrilamine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  1.10nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells by [3H]mesulergine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  501nMAssay Description:Binding affinity for human cloned Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  1.10nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells by [125I]R91150 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  36nMAssay Description:Binding affinity for human cloned Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  14nMAssay Description:Binding affinity for human cloned Dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  1.59E+3nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding affinity for rat Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  14nMAssay Description:Binding affinity for human cloned Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  45nMAssay Description:Binding affinity for human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  1.18E+3nMAssay Description:Binding affinity for human cloned Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50403974(CHEMBL84931)
Affinity DataIC50:  302nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed