BDBM50404089 CHEMBL131162

SMILES Clc1ccc(Cl)c(c1)C(=O)NCC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=MQAXGMKOSXBMHT-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50404089   

TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50404089(CHEMBL5267972)
Affinity DataIC50:  12nMAssay Description:pA2 value was calculated from dose-response plots generated by using different concentrations ranging between 1 and 10 uM antagonist.More data for this Ligand-Target Pair
In DepthDetails
TargetCholinesterase(Equus caballus (Horse))TBA
LigandPNGBDBM50404089(CHEMBL5267972)
Affinity DataIC50:  12nMAssay Description:In vitro antagonism against Alpha-1A adrenergic receptor using phenylephrine (PE) challenge in dog prostateMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM50404089(CHEMBL5267972)
Affinity DataIC50:  2.10E+4nMAssay Description:In vitro antagonism against Alpha-1A adrenergic receptor using phenylephrine (PE) challenge in rat vas deferensMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))TBA
LigandPNGBDBM50404089(CHEMBL5267972)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro antagonism against Alpha-1A adrenergic receptor using phenylephrine (PE) challenge in rat vas deferensMore data for this Ligand-Target Pair
In DepthDetails
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50404089(CHEMBL5267972)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro antagonism against Alpha-1A adrenergic receptor using phenylephrine (PE) challenge in dog prostateMore data for this Ligand-Target Pair
In DepthDetails