BDBM50404862 CROMOLYN SODIUM::Crolom::Cromoglicic Acid::Cromoglycic Acid::Cromolyn

SMILES OC(COc1cccc2oc(cc(=O)c12)C([O-])=O)COc1cccc2oc(cc(=O)c12)C([O-])=O

InChI Key InChIKey=IMZMKUWMOSJXDT-UHFFFAOYSA-L

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50404862   

TargetAlkaline phosphatase, germ cell type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50404862(CROMOLYN SODIUM | Crolom | Cromoglicic Acid | Crom...)
Affinity DataIC50: >1.60E+7nMAssay Description:50% inhibition of human placental alkaline phosphatase in the presence of 10 mM p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-coupled receptor GPR35(Rattus norvegicus)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50404862(CROMOLYN SODIUM | Crolom | Cromoglicic Acid | Crom...)
Affinity DataEC50:  986nMAssay Description:Agonist activity at rat GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, germ cell type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50404862(CROMOLYN SODIUM | Crolom | Cromoglicic Acid | Crom...)
Affinity DataIC50:  9.68E+6nMAssay Description:Concentration required for 50% inhibition of human leukocyte alkaline phosphatase in the presence of 10 mM p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50404862(CROMOLYN SODIUM | Crolom | Cromoglicic Acid | Crom...)
Affinity DataEC50:  1.26E+3nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Mus musculus)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50404862(CROMOLYN SODIUM | Crolom | Cromoglicic Acid | Crom...)
Affinity DataEC50:  4.84E+3nMAssay Description:Agonist activity at mouse GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed