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BDBM50406057 CHEMBL59544

SMILES: Clc1ccc(cc1Cl)C(CCNC(=N)NCCCc1cnc[nH]1)c1ccccc1

InChI Key: InChIKey=VZJQWRAJEFEHEY-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406057   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406057
PNG
(CHEMBL59544)
Show SMILES Clc1ccc(cc1Cl)C(CCNC(=N)NCCCc1cnc[nH]1)c1ccccc1
Show InChI InChI=1S/C22H25Cl2N5/c23-20-9-8-17(13-21(20)24)19(16-5-2-1-3-6-16)10-12-28-22(25)27-11-4-7-18-14-26-15-29-18/h1-3,5-6,8-9,13-15,19H,4,7,10-12H2,(H,26,29)(H3,25,27,28)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 195n/an/an/an/an/a



Freie Universit£t Berlin

Curated by ChEMBL


Assay Description
Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig.


J Med Chem 32: 1963-70 (1989)


Article DOI: 10.1021/jm00128a045
BindingDB Entry DOI: 10.7270/Q2BG2Q57
More data for this
Ligand-Target Pair