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BDBM50406170 CHEMBL101312

SMILES: Fc1ccccc1NC(=O)CCN1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=MQSSJGZUEXNJCQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406170   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406170
PNG
(CHEMBL101312)
Show SMILES Fc1ccccc1NC(=O)CCN1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H24FN3O/c21-18-8-4-5-9-19(18)22-20(25)10-11-23-12-14-24(15-13-23)16-17-6-2-1-3-7-17/h1-9H,10-16H2,(H,22,25)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.32E+3n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum


J Med Chem 33: 2970-6 (1990)


Article DOI: 10.1021/jm00173a011
BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair