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BDBM50406289 CHEMBL141377

SMILES: CC(C)N(C(C)C)c1nc2ccccc2c(=O)o1

InChI Key: InChIKey=VZVOLFPUJZTOGM-UHFFFAOYSA-N

Data: 1 KI  1 Koff  1 Kon

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406289   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukocyte elastase


(Homo sapiens (Human))
BDBM50406289
PNG
(CHEMBL141377)
Show SMILES CC(C)N(C(C)C)c1nc2ccccc2c(=O)o1
Show InChI InChI=1S/C14H18N2O2/c1-9(2)16(10(3)4)14-15-12-8-6-5-7-11(12)13(17)18-14/h5-10H,1-4H3
PDB
MMDB

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PC sid
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Similars

Article
PubMed
2.51E+3n/an/an/an/a 0.00263 1.02E+3n/an/a



Syntex Research

Curated by ChEMBL


Assay Description
Component deacylation rate constant for interaction with human leukocyte elastase


J Med Chem 33: 464-79 (1990)

Checked by Author
Article DOI: 10.1021/jm00164a002
BindingDB Entry DOI: 10.7270/Q2PR7X6X
More data for this
Ligand-Target Pair