BDBM50406811 CHEMBL4175060

SMILES Cc1noc(C)c1-c1ccc2NC(=O)[C@@H](CC3CC3)Oc2c1

InChI Key InChIKey=CMSYOXFBNZPEJB-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50406811   

TargetBromodomain-containing protein 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50406811(CHEMBL4175060)
Affinity DataIC50: 100nMAssay Description:Inhibition of His6-tagged human BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) using biotinylated-H4KAc4 as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50406811(CHEMBL4175060)
Affinity DataKd:  110nMAssay Description:Binding affinity to His6-tagged human BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50406811(CHEMBL4175060)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of His6-tagged human CREBBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) using biotinylated-H4KAc4 as substrate by Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed