BDBM50408465 CHEMBL120546

SMILES FC(F)(F)c1cc(COCC2(CCCNC2)c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=JCQSGNUMUCYWTO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50408465   

TargetSubstance-P receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50408465(CHEMBL120546)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]substance P from human recombinant NK1 receptor expressed in human U373 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50408465(CHEMBL120546)
Affinity DataIC50:  19.9nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50408465(CHEMBL120546)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed