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BDBM50408467 CHEMBL121094::MEN-10725

SMILES: CN(Cc1ccccc1)C(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@@H]1CCCC[C@@H]1NC(=O)c1c[nH]c2ccccc12

InChI Key: InChIKey=LOQZSBGQNIRLDR-RDKKHIPBSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408467   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Substance-P receptor


(Homo sapiens (Human))
BDBM50408467
PNG
(CHEMBL121094 | MEN-10725)
Show SMILES CN(Cc1ccccc1)C(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@@H]1CCCC[C@@H]1NC(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C37H38N4O3/c1-41(24-25-11-3-2-4-12-25)37(44)34(22-26-19-20-27-13-5-6-14-28(27)21-26)40-35(42)30-16-8-10-18-33(30)39-36(43)31-23-38-32-17-9-7-15-29(31)32/h2-7,9,11-15,17,19-21,23,30,33-34,38H,8,10,16,18,22,24H2,1H3,(H,39,43)(H,40,42)/t30-,33+,34+/m1/s1
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MMDB

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Similars

Article
PubMed
n/an/a 12.6n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Binding affinity was measured against the Tachykinin receptor 1 in human IM-9 cells using [3H]SP as ligand.


J Med Chem 41: 3609-23 (1998)


Article DOI: 10.1021/jm9700171
BindingDB Entry DOI: 10.7270/Q2V1260Z
More data for this
Ligand-Target Pair