BDBM50408840 CHEMBL5271662

SMILES OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1ccc(N(C(=O)c2c(Cl)cc(Cl)cc2Cl)C(=O)c2c(Cl)cc(Cl)cc2Cl)c(Cl)c1

InChI Key InChIKey=UVJIIBHGVCKZJY-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50408840   

TargetNAD-dependent protein deacylase sirtuin-6(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50408840(CHEMBL5271662)
Affinity DataKi:  1.34E+4nMAssay Description:Competitive inhibition of SIRT6 (unknown origin) demyristoylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50408840(CHEMBL5271662)
Affinity DataEC50:  1.55E+4nMAssay Description:Activation of SIRT6 (unknown origin) deacetylase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed