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BDBM50408947 CHEMBL103211

SMILES: CCOC(=O)c1c(C)[nH]c(\C=C2\C(=O)Nc3ccccc23)c1C

InChI Key: InChIKey=PMUJUSJUVIXDQC-UKTHLTGXSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408947   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM50408947
PNG
(CHEMBL103211)
Show SMILES CCOC(=O)c1c(C)[nH]c(\C=C2\C(=O)Nc3ccccc23)c1C
Show InChI InChI=1S/C18H18N2O3/c1-4-23-18(22)16-10(2)15(19-11(16)3)9-13-12-7-5-6-8-14(12)20-17(13)21/h5-9,19H,4H2,1-3H3,(H,20,21)/b13-9+
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MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 71n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibitory activity against vascular endothelial growth factor receptor 2 (FLK1)


J Med Chem 43: 3020-32 (2000)


Article DOI: 10.1021/jm990609e
BindingDB Entry DOI: 10.7270/Q2HM59P2
More data for this
Ligand-Target Pair